Gastrointestinal ve Pankreas Nöroendokrin Tümörlerine Güncel Histopatolojik Yaklaşım
References
Patel N, Barbieri A, Gibson J. Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas. Surg Pathol Clin. 2019;12(4):1021-44.
Pearse AG. The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. J Histochem Cytochem. 1969;17(5):303-13.
Rosai J. The origin of neuroendocrine tumors and the neural crest saga. Mod Pathol. 2011;24 Suppl 2:S53-7.
Klöppel G, Rindi G, Anlauf M, et al. Site-specific biology and pathology of gastroenteropancreatic neuroendocrine tumors. Virchows Arch. 2007;451 Suppl 1:S9-27.
Wiedenmann B, John M, Ahnert-Hilger G, et al. Molecular and cell biological aspects of neuroendocrine tumors of the gastroenteropancreatic system. Journal of Molecular Medicine. 1998;76:637-47.
Nagtegaal ID, Odze RD, Klimstra D, et al. The 2019 WHO classification of tumours of the digestive system. Histopathology. 2020;76(2):182-8.
Odze RD, Goldblum JR. Odze and Goldblum surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas: Elsevier Health Sciences; 2023. 951 p.
Das S, Dasari A. Epidemiology, Incidence, and Prevalence of Neuroendocrine Neoplasms: Are There Global Differences? Curr Oncol Rep. 2021;23(4):43.
Lawrence B, Gustafsson BI, Chan A, et al. The epidemiology of gastroenteropancreatic neuroendocrine tumors. Endocrinol Metab Clin North Am. 2011;40(1):1-18, vii.
Rindi G. Nomenclature and classification of neuroendocrine neoplasms of the digestive system. WHO classification of tumours of the digestive system. 2010:13-4.
Moreira RK, Washington K. Pathology of Gastrointestinal Neuroendocrine Tumors: An Update. Surg Pathol Clin. 2010;3(2):327-47.
Toor D, Loree JM, Gao ZH, Wang G, Zhou C. Mixed neuroendocrine-non-neuroendocrine neoplasms of the digestive system: A mini-review. World J Gastroenterol. 2022;28(19):2076-87.
de Mestier L, Cros J, Neuzillet C, et al. Digestive System Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms. Neuroendocrinology. 2017;105(4):412-25.
La Rosa S. Challenges in High-grade Neuroendocrine Neoplasms and Mixed Neuroendocrine/Non-neuroendocrine Neoplasms. Endocr Pathol. 2021;32(2):245-57.
Park JY, Ryu MH, Park YS, et al. Prognostic significance of neuroendocrine components in gastric carcinomas. Eur J Cancer. 2014;50(16):2802-9.
Jiang SX, Mikami T, Umezawa A, Saegusa M, Kameya T, Okayasu I. Gastric large cell neuroendocrine carcinomas: a distinct clinicopathologic entity. Am J Surg Pathol. 2006;30(8):945-53.
Klimstra D, Klöppel G, La Rosa S, Rindi G. Classification of neuroendocrine neoplasms of the digestive system. WHO Classification of tumours, 5th Edition Digestive system tumours. 2019:16-9.
Dasari A, Shen C, Halperin D, et al. Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States. JAMA Oncol. 2017;3(10):1335-42.
Chai SM, Brown IS, Kumarasinghe MP. Gastroenteropancreatic neuroendocrine neoplasms: selected pathology review and molecular updates. Histopathology. 2018;72(1):153-67.
Voss SM, Riley MP, Lokhandwala PM, et al. Mitotic count by phosphohistone H3 immunohistochemical staining predicts survival and improves interobserver reproducibility in well-differentiated neuroendocrine tumors of the pancreas. Am J Surg Pathol. 2015;39(1):13-24.
Tang LH, Gonen M, Hedvat C, et al. Objective quantification of the Ki67 proliferative index in neuroendocrine tumors of the gastroenteropancreatic system: a comparison of digital image analysis with manual methods. Am J Surg Pathol. 2012;36(12):1761-70.
Sappenfield R, Gonzalez IA, Cao D, et al. Well-differentiated rectal neuroendocrine tumors: analysis of histology, including insulinoma-associated protein 1 expression, and biologic behavior, involving a large cohort of 94 cases. Hum Pathol. 2020;104:66-72.
Volante M, Grillo F, Massa F, et al. Neuroendocrine neoplasms of the appendix, colon and rectum. Pathologica. 2021;113(1):19-27.
Assarzadegan N, Montgomery E. What is New in the 2019 World Health Organization (WHO) Classification of Tumors of the Digestive System: Review of Selected Updates on Neuroendocrine Neoplasms, Appendiceal Tumors, and Molecular Testing. Arch Pathol Lab Med. 2021;145(6):664-77.
Perez K, Chan J. Treatment of Gastroenteropancreatic Neuroendocrine Tumors. Surg Pathol Clin. 2019;12(4):1045-53.
Butturini G, Bettini R, Missiaglia E, et al. Predictive factors of efficacy of the somatostatin analogue octreotide as first line therapy for advanced pancreatic endocrine carcinoma. Endocr Relat Cancer. 2006;13(4):1213-21.
Cives M, Strosberg JR. Gastroenteropancreatic Neuroendocrine Tumors. CA Cancer J Clin. 2018;68(6):471-87.
Pearse AG. The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept. J Histochem Cytochem. 1969;17(5):303-13.
Rosai J. The origin of neuroendocrine tumors and the neural crest saga. Mod Pathol. 2011;24 Suppl 2:S53-7.
Klöppel G, Rindi G, Anlauf M, et al. Site-specific biology and pathology of gastroenteropancreatic neuroendocrine tumors. Virchows Arch. 2007;451 Suppl 1:S9-27.
Wiedenmann B, John M, Ahnert-Hilger G, et al. Molecular and cell biological aspects of neuroendocrine tumors of the gastroenteropancreatic system. Journal of Molecular Medicine. 1998;76:637-47.
Nagtegaal ID, Odze RD, Klimstra D, et al. The 2019 WHO classification of tumours of the digestive system. Histopathology. 2020;76(2):182-8.
Odze RD, Goldblum JR. Odze and Goldblum surgical Pathology of the GI Tract, Liver, Biliary Tract and Pancreas: Elsevier Health Sciences; 2023. 951 p.
Das S, Dasari A. Epidemiology, Incidence, and Prevalence of Neuroendocrine Neoplasms: Are There Global Differences? Curr Oncol Rep. 2021;23(4):43.
Lawrence B, Gustafsson BI, Chan A, et al. The epidemiology of gastroenteropancreatic neuroendocrine tumors. Endocrinol Metab Clin North Am. 2011;40(1):1-18, vii.
Rindi G. Nomenclature and classification of neuroendocrine neoplasms of the digestive system. WHO classification of tumours of the digestive system. 2010:13-4.
Moreira RK, Washington K. Pathology of Gastrointestinal Neuroendocrine Tumors: An Update. Surg Pathol Clin. 2010;3(2):327-47.
Toor D, Loree JM, Gao ZH, Wang G, Zhou C. Mixed neuroendocrine-non-neuroendocrine neoplasms of the digestive system: A mini-review. World J Gastroenterol. 2022;28(19):2076-87.
de Mestier L, Cros J, Neuzillet C, et al. Digestive System Mixed Neuroendocrine-Non-Neuroendocrine Neoplasms. Neuroendocrinology. 2017;105(4):412-25.
La Rosa S. Challenges in High-grade Neuroendocrine Neoplasms and Mixed Neuroendocrine/Non-neuroendocrine Neoplasms. Endocr Pathol. 2021;32(2):245-57.
Park JY, Ryu MH, Park YS, et al. Prognostic significance of neuroendocrine components in gastric carcinomas. Eur J Cancer. 2014;50(16):2802-9.
Jiang SX, Mikami T, Umezawa A, Saegusa M, Kameya T, Okayasu I. Gastric large cell neuroendocrine carcinomas: a distinct clinicopathologic entity. Am J Surg Pathol. 2006;30(8):945-53.
Klimstra D, Klöppel G, La Rosa S, Rindi G. Classification of neuroendocrine neoplasms of the digestive system. WHO Classification of tumours, 5th Edition Digestive system tumours. 2019:16-9.
Dasari A, Shen C, Halperin D, et al. Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States. JAMA Oncol. 2017;3(10):1335-42.
Chai SM, Brown IS, Kumarasinghe MP. Gastroenteropancreatic neuroendocrine neoplasms: selected pathology review and molecular updates. Histopathology. 2018;72(1):153-67.
Voss SM, Riley MP, Lokhandwala PM, et al. Mitotic count by phosphohistone H3 immunohistochemical staining predicts survival and improves interobserver reproducibility in well-differentiated neuroendocrine tumors of the pancreas. Am J Surg Pathol. 2015;39(1):13-24.
Tang LH, Gonen M, Hedvat C, et al. Objective quantification of the Ki67 proliferative index in neuroendocrine tumors of the gastroenteropancreatic system: a comparison of digital image analysis with manual methods. Am J Surg Pathol. 2012;36(12):1761-70.
Sappenfield R, Gonzalez IA, Cao D, et al. Well-differentiated rectal neuroendocrine tumors: analysis of histology, including insulinoma-associated protein 1 expression, and biologic behavior, involving a large cohort of 94 cases. Hum Pathol. 2020;104:66-72.
Volante M, Grillo F, Massa F, et al. Neuroendocrine neoplasms of the appendix, colon and rectum. Pathologica. 2021;113(1):19-27.
Assarzadegan N, Montgomery E. What is New in the 2019 World Health Organization (WHO) Classification of Tumors of the Digestive System: Review of Selected Updates on Neuroendocrine Neoplasms, Appendiceal Tumors, and Molecular Testing. Arch Pathol Lab Med. 2021;145(6):664-77.
Perez K, Chan J. Treatment of Gastroenteropancreatic Neuroendocrine Tumors. Surg Pathol Clin. 2019;12(4):1045-53.
Butturini G, Bettini R, Missiaglia E, et al. Predictive factors of efficacy of the somatostatin analogue octreotide as first line therapy for advanced pancreatic endocrine carcinoma. Endocr Relat Cancer. 2006;13(4):1213-21.
Cives M, Strosberg JR. Gastroenteropancreatic Neuroendocrine Tumors. CA Cancer J Clin. 2018;68(6):471-87.
Pages
99-114
Published
April 5, 2023
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Koyuncuer A. Gastrointestinal ve Pankreas Nöroendokrin Tümörlerine Güncel Histopatolojik Yaklaşım. In: Alabaz Ö, editor. Güncel Genel Cerrahi Çalışmaları IV [Internet]. Türkiye: Academician Publishing Book DOI Portal; 2023 [cited 2026 Jul. 16]. pp. 99-114. Available from: https://omp35.books.akademisyen.net/index.php/akya/catalog/book/2553/chapter/12758