Apendiks Mukoseli: Klinik, Görüntüleme ve Yönetimi
Synopsis
Apendiks mukoseli apendiks lümeninin çeşitli nedenlerle müsinöz içerikle dolduğu ve genişlediği, nadir olarak karşımıza çıkan bir durumdur. Apendiks mukoseli olan hastaların çoğu asemptomatiktir. Bununla birlikte apendiks mukoseli perfore olduğunda psödomiksoma peritoneiye yol açabilmekte ve hayatı tehdit edici bir hale gelebilmektedir. Radyolojik görüntülemede apendiks mukoseli genellikle çekum ile bağlantılı, düzgün sınırlı, elonge kistik bir yapı şeklinde görülür. Apendiks mukoselinin tedavisinde cerrahi tedavi önerilmektedir. Bu bölümde apendiks mukoseli klinik, histopatolojik ve radyolojik yönleriyle değerlendirilecektir.
References
Higa E, Rosai J, Pizzimbono CA, Wise L. Mucosal hyperplasia, mucinous cystadenoma, and mucinous cystadenocarcinoma of the appendix. A re-evaluation of appendiceal “mucocele.” Cancer. 1973;32(6):1525–41.
Rokitansky CF. A manual of pathological anatomy. Vol 2. English translation of the Vienna edition (1842). Philadelphia: Blancard and Lea, 1855:89.
Filho JGDA, Lira EF De. Mucocele of the appendix - appendectomy or colectomy? Journal of Coloproctology. 2011;31(3):276–84.
Saad EA, Elsamani EY, AbdElrahim WE, Elsiddig KE, Khalil EAG. Surgical treatment of mucocele of the appendix: a systematic review and case report. Journal of Surgical Case Reports. 2018;2018(6):1–3.
Güner Z, Schmidt U, Dahlke MH, Schlitt HJ, Klempnauer J, Piso P. Cytoreductive surgery and intraperitoneal chemotherapy for pseudomyxoma peritonei. International Journal of Colorectal Disease. 2005;20(2):155–60.
Woodruff R, McDonald J. Benign and malignant cystic tumors of the appendix. Surgery, Gynecology and Obstetrics. 1940;71:751-5.
Misdraji J, Yantiss RK, Graeme-Cook FM, Balis UJ, Young RH. Appendiceal mucinous neoplasms: A clinicopathologic analysis of 107 cases. The American Journal of Surgical Pathology. 2003;27(8):1089–103.
Stocchi L, Wolff BG, Larson DR, Harrington JR, Dayton MT, Galandiuk S. Surgical treatment of appendiceal mucocele. The Archives of Surgery. 2003;138(6):585–90.
Hines JJ, Paek GK, Lee P, Wu L, Katz DS. Beyond appendicitis; radiologic review of unusual and rare pathology of the appendix. Abdominal Radiology. 2016;41(3):568–81.
Persaud T, Swan N, Torreggiani WC. Best cases from the AFIP: Giant mucinous cystadenoma of the appendix. Radiographics. 2007;27(2):553–7.
Carr NJ, McCarthy WF, Sobin LH. Epithelial noncarcinoid tumors and tumor‐like lesions of the appendix. A clinicopathologic study of 184 patients with a multivariate analysis of prognostic factors. Cancer. 1995;75(3):757–68.
Ronnett CM, Zahn CM, Kurman RJ, Kass ME, Sugarbaker PH, Shmookler BM. Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis. A clinicopathologic analysis of 109 cases with emphasis on distinghishing pathologic features, site of origin, prognosis, and relationship to pseudomyxoma peritonei. The American Journal of Surgical Pathology. 1995;19(12):1390-408.
Pickhardt PJ, Levy AD, Rohrmann CA, Kende AI. Primary Neoplasms of the Appendix: Radiologic Spectrum of Disease with Pathologic Correlation. Radiographics. 2003;23(3):645–62.
Deans GT, Spence RAJ. Neoplastic lesions of the appendix. British Journal of Surgery. 1995;82(3):299–306.
Carr NJ, Sobin LH. Unusual tumors of the appendix and pseudomyxoma peritonei. Seminars in Diagnostic Pathology. 1996; 13:314–325.).
Pehlivanlı F, Karaca G, Daphan ÇE, Eroğlu O, Vural S, Coşkun F. Karın Ağrısının Nadi̇r Bi̇r Nedeni̇:Apendi̇ks Mukosel Olgu Sunumu. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi. 2018;20(3):345–8.
Zanati SA, Martin JA, Baker JP, Streutker CJ, Marcon NE. Colonoscopic diagnosis of mucocele of the appendix. Gastrointestinal Endoscopy. 2005;62(3):452–6.
Orita K, Tanaka N. Appendiceal Mucocele with Concomitant Colonic Cancer. Diseases of the Colon & Rectum. 1996 Feb;39(2):232-6.
Zuzarte JC, Liu YC, Cohen AM. Fine needle aspiration cytology of appendiceal mucinous cystadenoma: A case report. Acta Cytologica. 1996;40(2):327–30.
Madwed D, Mindelzun R, Jeffrey RB. Mucocele of the appendix: Imaging findings. American Journal of Roentgenology. 1992;159(1):69–72.
Tirumani SH, Fraser-Hill M, Auer R, Shabana W, Walsh C, Lee F, et al. Mucinous neoplasms of the appendix: A current comprehensive clinicopathologic and imaging review. Cancer Imaging. 2013;13(1):14–25.
Sasaki K, Ishida H, Komatsuda T, Suzuki T, Konno K, Ohtaka M, et al. Appendiceal mucocele: Sonographic findings. Abdominal Imaging. 2003;28(1):15–8.
Kim SH, Lim HK, Lee WJ, Lim JH, Byun JY. Mucocele of the appendix: Ultrasonographic and CT findings. Abdominal Imaging. 1998;23(3):292–6.
Koga H, Aoyagi K, Honda H, Fujishima M. Appendiceal mucocele: sonographic and MR imaging findings. AJR.1995; 165:1552.
Lim HK, Lee WJ, Kim SH, Kim B, Cho JM, Byum JY. Primary mucinous cystadenocarcinoma of the appendix: CT findings. American Journal of Roentgenology. 1999; 173:1071–1074.
Honnef I, Moschopulos M, Roeren T. Best cases from the AFIP appendiceal mucinous cystadenoma. Radiographics. 2008;28(5):1524–7.
González Moreno S, Shmookler BM, Sugarbaker PH. Appendiceal mucocele: Contraindication to laparoscopic appendectomy. Surgical Endoscopy. 1998;12(9):1177–9.
Malya FU, Hasbahceci M, Serter A, Cipe G, Karatepe O, Kocakoc E, et al. Appendiceal mucocele: Clinical and imaging features of 14 cases. Chirurgia. 2014;109(6):788–93.
Rokitansky CF. A manual of pathological anatomy. Vol 2. English translation of the Vienna edition (1842). Philadelphia: Blancard and Lea, 1855:89.
Filho JGDA, Lira EF De. Mucocele of the appendix - appendectomy or colectomy? Journal of Coloproctology. 2011;31(3):276–84.
Saad EA, Elsamani EY, AbdElrahim WE, Elsiddig KE, Khalil EAG. Surgical treatment of mucocele of the appendix: a systematic review and case report. Journal of Surgical Case Reports. 2018;2018(6):1–3.
Güner Z, Schmidt U, Dahlke MH, Schlitt HJ, Klempnauer J, Piso P. Cytoreductive surgery and intraperitoneal chemotherapy for pseudomyxoma peritonei. International Journal of Colorectal Disease. 2005;20(2):155–60.
Woodruff R, McDonald J. Benign and malignant cystic tumors of the appendix. Surgery, Gynecology and Obstetrics. 1940;71:751-5.
Misdraji J, Yantiss RK, Graeme-Cook FM, Balis UJ, Young RH. Appendiceal mucinous neoplasms: A clinicopathologic analysis of 107 cases. The American Journal of Surgical Pathology. 2003;27(8):1089–103.
Stocchi L, Wolff BG, Larson DR, Harrington JR, Dayton MT, Galandiuk S. Surgical treatment of appendiceal mucocele. The Archives of Surgery. 2003;138(6):585–90.
Hines JJ, Paek GK, Lee P, Wu L, Katz DS. Beyond appendicitis; radiologic review of unusual and rare pathology of the appendix. Abdominal Radiology. 2016;41(3):568–81.
Persaud T, Swan N, Torreggiani WC. Best cases from the AFIP: Giant mucinous cystadenoma of the appendix. Radiographics. 2007;27(2):553–7.
Carr NJ, McCarthy WF, Sobin LH. Epithelial noncarcinoid tumors and tumor‐like lesions of the appendix. A clinicopathologic study of 184 patients with a multivariate analysis of prognostic factors. Cancer. 1995;75(3):757–68.
Ronnett CM, Zahn CM, Kurman RJ, Kass ME, Sugarbaker PH, Shmookler BM. Disseminated peritoneal adenomucinosis and peritoneal mucinous carcinomatosis. A clinicopathologic analysis of 109 cases with emphasis on distinghishing pathologic features, site of origin, prognosis, and relationship to pseudomyxoma peritonei. The American Journal of Surgical Pathology. 1995;19(12):1390-408.
Pickhardt PJ, Levy AD, Rohrmann CA, Kende AI. Primary Neoplasms of the Appendix: Radiologic Spectrum of Disease with Pathologic Correlation. Radiographics. 2003;23(3):645–62.
Deans GT, Spence RAJ. Neoplastic lesions of the appendix. British Journal of Surgery. 1995;82(3):299–306.
Carr NJ, Sobin LH. Unusual tumors of the appendix and pseudomyxoma peritonei. Seminars in Diagnostic Pathology. 1996; 13:314–325.).
Pehlivanlı F, Karaca G, Daphan ÇE, Eroğlu O, Vural S, Coşkun F. Karın Ağrısının Nadi̇r Bi̇r Nedeni̇:Apendi̇ks Mukosel Olgu Sunumu. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi. 2018;20(3):345–8.
Zanati SA, Martin JA, Baker JP, Streutker CJ, Marcon NE. Colonoscopic diagnosis of mucocele of the appendix. Gastrointestinal Endoscopy. 2005;62(3):452–6.
Orita K, Tanaka N. Appendiceal Mucocele with Concomitant Colonic Cancer. Diseases of the Colon & Rectum. 1996 Feb;39(2):232-6.
Zuzarte JC, Liu YC, Cohen AM. Fine needle aspiration cytology of appendiceal mucinous cystadenoma: A case report. Acta Cytologica. 1996;40(2):327–30.
Madwed D, Mindelzun R, Jeffrey RB. Mucocele of the appendix: Imaging findings. American Journal of Roentgenology. 1992;159(1):69–72.
Tirumani SH, Fraser-Hill M, Auer R, Shabana W, Walsh C, Lee F, et al. Mucinous neoplasms of the appendix: A current comprehensive clinicopathologic and imaging review. Cancer Imaging. 2013;13(1):14–25.
Sasaki K, Ishida H, Komatsuda T, Suzuki T, Konno K, Ohtaka M, et al. Appendiceal mucocele: Sonographic findings. Abdominal Imaging. 2003;28(1):15–8.
Kim SH, Lim HK, Lee WJ, Lim JH, Byun JY. Mucocele of the appendix: Ultrasonographic and CT findings. Abdominal Imaging. 1998;23(3):292–6.
Koga H, Aoyagi K, Honda H, Fujishima M. Appendiceal mucocele: sonographic and MR imaging findings. AJR.1995; 165:1552.
Lim HK, Lee WJ, Kim SH, Kim B, Cho JM, Byum JY. Primary mucinous cystadenocarcinoma of the appendix: CT findings. American Journal of Roentgenology. 1999; 173:1071–1074.
Honnef I, Moschopulos M, Roeren T. Best cases from the AFIP appendiceal mucinous cystadenoma. Radiographics. 2008;28(5):1524–7.
González Moreno S, Shmookler BM, Sugarbaker PH. Appendiceal mucocele: Contraindication to laparoscopic appendectomy. Surgical Endoscopy. 1998;12(9):1177–9.
Malya FU, Hasbahceci M, Serter A, Cipe G, Karatepe O, Kocakoc E, et al. Appendiceal mucocele: Clinical and imaging features of 14 cases. Chirurgia. 2014;109(6):788–93.
Pages
53-62
Published
April 3, 2023
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Koyun M. Apendiks Mukoseli: Klinik, Görüntüleme ve Yönetimi. In: Kaya Ö, editor. Güncel Radyoloji Çalışmaları III [Internet]. Türkiye: Academician Publishing Book DOI Portal; 2023 [cited 2026 Jul. 16]. pp. 53-62. Available from: https://omp35.books.akademisyen.net/index.php/akya/catalog/book/2545/chapter/12702