İnflamatuar Romatizmal Hastalıklarda Nosiplastik Ağrı
Synopsis
Nosiplastik ağrı, tanımlanabilir sinir dokusu hasarı olmayan ağrı; santral sensitizasyon ve nöronal disregülasyondan kaynaklandığı düşünülen ağrı olarak tanımlanmaktadır. Nosiplastik ağrı için santral ağrı veya santralize ağrı terimi de kullanılabilmektedir. İnflamatuar romatizmal hastalıkları olan bireylerde inflamasyonun ağrı ile ilişkisi tartışılmazdır. Fakat son zamanlarda bu hasta grubunda zamanla gelişen nosiplastik ağrının, inflamasyon kontrol altına alınsa bile hastada ağrı varlığını devam ettirebildiği bildirilmiştir. Bu hasta grubunda nosiplastik ağrının zamanında fark edilmemesi gereksiz DMARD değişikliklerine ve / veya hastanın yaşam kalitesinde kötüleşmeye neden olabilmektedir.
References
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Isagulyan ED, Makashova ES, Myasnikova LK, et al. Psychogenic (nociplastic) pain: Current state of diagnosis, treatment options, and potentials of neurosurgical management. Progress in brain research. 2022;272(1):105-23.
Nijs J, Leysen L, Vanlauwe J, et al. Treatment of central sensitization in patients with chronic pain: time for change? Expert opinion on pharmacotherapy. 2019;20(16):1961-70.
Bailly F, Cantagrel A, Bertin P, et al. Part of pain labelled neuropathic in rheumatic disease might be rather nociplastic. RMD Open. 2020;6(2):e001326.
Schneider J, Patterson M, Jimenez XF. Beyond depression: Other uses for tricyclic antidepressants. Cleveland Clinic journal of medicine. 2019;86(12):807-14.
Patetsos E, Horjales-Araujo E. Treating Chronic Pain with SSRIs: What Do We Know? Pain Res Manag. 2016;2016:2020915-.
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Sumpton JE, Moulin DE. Fibromyalgia. Handbook of clinical neurology. 2014;119:513-27.
Nijs J, Malfliet A, Ickmans K, et al. Treatment of central sensitization in patients with 'unexplained' chronic pain: an update. Expert opinion on pharmacotherapy. 2014;15(12):1671-83.
Hall OT, Teater J, Rood KM, et al. Central sensitization in opioid use disorder: a novel application of the American College of Rheumatology Fibromyalgia Survey Criteria. Pain reports. 2022;7(4):e1016.
Kaka U, Rahman NA, Abubakar AA, et al. Pre-emptive multimodal analgesia with tramadol and ketamine-lidocaine infusion for suppression of central sensitization in a dog model of ovariohysterectomy. Journal of pain research. 2018;11:743-52.
Scholz J, Finnerup NB, Attal N, et al. The IASP classification of chronic pain for ICD-11: chronic neuropathic pain. Pain. 2019;160(1):53-9.
Watson JC, Sandroni P. Central Neuropathic Pain Syndromes. Mayo Clinic proceedings. 2016;91(3):372-85.
Arnold LM, Choy E, Clauw DJ, et al. Fibromyalgia and Chronic Pain Syndromes: A White Paper Detailing Current Challenges in the Field. The Clinical journal of pain. 2016;32(9):737-46.
Ji RR, Nackley A, Huh Y, et al. Neuroinflammation and Central Sensitization in Chronic and Widespread Pain. Anesthesiology. 2018;129(2):343-66.
Cao Y, Fan D, Yin Y. Pain Mechanism in Rheumatoid Arthritis: From Cytokines to Central Sensitization. Mediators of inflammation. 2020;2020:2076328.
Phillips K, Clauw DJ. Central pain mechanisms in the rheumatic diseases: future directions. Arthritis and rheumatism. 2013;65(2):291-302.
Sanzarello I, Merlini L, Rosa MA, et al. Central sensitization in chronic low back pain: A narrative review. Journal of back and musculoskeletal rehabilitation. 2016;29(4):625-33.
Fitzcharles MA, Cohen SP, Clauw DJ, Littlejohn G, Usui C, Häuser W. Nociplastic pain: towards an understanding of prevalent pain conditions. Lancet (London, England). 2021;397(10289):2098-110.
Düzce Keleş E, Birtane M, Ekuklu G, et al. Validity and reliability of the Turkish version of the central sensitization inventory. Archives of rheumatology. 2021;36(4):518-26.
Ferro Moura Franco K, Lenoir D, Dos Santos Franco YR, et al. Prescription of exercises for the treatment of chronic pain along the continuum of nociplastic pain: A systematic review with meta-analysis. European journal of pain (London, England). 2021;25(1):51-70.
Isagulyan ED, Makashova ES, Myasnikova LK, et al. Psychogenic (nociplastic) pain: Current state of diagnosis, treatment options, and potentials of neurosurgical management. Progress in brain research. 2022;272(1):105-23.
Nijs J, Leysen L, Vanlauwe J, et al. Treatment of central sensitization in patients with chronic pain: time for change? Expert opinion on pharmacotherapy. 2019;20(16):1961-70.
Bailly F, Cantagrel A, Bertin P, et al. Part of pain labelled neuropathic in rheumatic disease might be rather nociplastic. RMD Open. 2020;6(2):e001326.
Schneider J, Patterson M, Jimenez XF. Beyond depression: Other uses for tricyclic antidepressants. Cleveland Clinic journal of medicine. 2019;86(12):807-14.
Patetsos E, Horjales-Araujo E. Treating Chronic Pain with SSRIs: What Do We Know? Pain Res Manag. 2016;2016:2020915-.
van Rensburg R, Reuter H. An overview of analgesics - anticonvulsants, antidepressants, and other medications (Part 3). South African Family Practice. 2019. 2019:5
Yüksel N. Duloksetin: Klinik Kullanımı. Klinik Psikiyatri 2012(Supp: 1):9-16.
Sumpton JE, Moulin DE. Fibromyalgia. Handbook of clinical neurology. 2014;119:513-27.
Nijs J, Malfliet A, Ickmans K, et al. Treatment of central sensitization in patients with 'unexplained' chronic pain: an update. Expert opinion on pharmacotherapy. 2014;15(12):1671-83.
Hall OT, Teater J, Rood KM, et al. Central sensitization in opioid use disorder: a novel application of the American College of Rheumatology Fibromyalgia Survey Criteria. Pain reports. 2022;7(4):e1016.
Kaka U, Rahman NA, Abubakar AA, et al. Pre-emptive multimodal analgesia with tramadol and ketamine-lidocaine infusion for suppression of central sensitization in a dog model of ovariohysterectomy. Journal of pain research. 2018;11:743-52.
Pages
131-138
Published
April 3, 2023
Copyright (c) 2023 Academician Book Portal
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1.
Okçu M. İnflamatuar Romatizmal Hastalıklarda Nosiplastik Ağrı. In: Kelle B, editor. Fizik Tedavi ve Rehabilitasyonda Güncel Konular [Internet]. Türkiye: Academician Publishing Book DOI Portal; 2023 [cited 2026 Jul. 16]. pp. 131-8. Available from: https://omp35.books.akademisyen.net/index.php/akya/catalog/book/2533/chapter/13797
