Crafting Tomorrow’s Diagnostics: Metal Nanoparticles in Biosensors – Types, Synthesis, and Future Frontiers in Health, Environment, and Food Safety
Özet
This chapter offers an in-depth exploration of the incorporation of metal nanoparticles (MNPs) into biosensors, showcasing their pivotal role in revolutionizing diagnostic technologies across a range of sectors, including healthcare, environmental monitoring, and food safety. The unique physicochemical properties of MNPs such as their high surface area-to-volume ratio, distinctive optical and electrical behaviors, and catalytic potential have made them indispensable in developing highly sensitive and specific biosensing platforms. The chapter systematically categorizes the various types of nanomaterials used in biosensors, including gold, silver, palladium, platinum, copper, nickel, iron oxide, zinc oxide and titanium oxide nanoparticles, and highlights their applications in critical areas such as real-time disease detection, pollutant monitoring, and foodborne pathogen identification. It also delves into the synthesis methods as chemical reduction, green synthesis, polyol process, sol-gel method, microwave-assisted, laser ablation, seed-mediated growth, photochemical reduction, electrochemical reduction, sonochemical reduction, hydrothermal and solvothermal, Moreover, the chapter examines the technical, regulatory, and commercialization challenges that hinder the broader adoption of these technologies, particularly in ensuring reproducibility, stability, and scalability. Looking forward, the chapter discusses emerging trends, including innovations in point-of-care diagnostics and the integration of artificial intelligence with biosensor platforms, which promise to propel the next generation of biosensing technologies. By addressing these challenges and capitalizing on future opportunities, MNP-based biosensors have the potential to significantly enhance global public health outcomes, environmental sustainability, and food safety.
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