Akut İskemik İnmeye Yaklaşım
References
GBD 2019 Stroke Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet Neurol. 2021;20(10):795–820.
Fisher M, Bastan B. Identifying and utilizing the ischemic penumbra. Neurology 2012;79:S79–85.
Hurford R, Sekhar A, Hughes TAT, Muir KW. Diagnosis and management of acute ischaemic stroke. Pract Neurol. 2020 Aug;20(4):304-316. doi: 10.1136/practneurol-2020-002557.
Hankey GJ. Stroke. Lancet 2017;389:641–54.
Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals from the American Heart Associa- tion/American Stroke Association. Stroke 2019;50: e344–418.
Brazzelli M, Shuler K, Quayyum Z, et al. Clinical and imaging services for TIA and minor stroke: results of two surveys of practice across the UK. BMJ Open 2013;3(8).
Wardlaw JM, Seymour J, Cairns J, et al. Immediate computed tomography scanning of acute stroke is cost-effective and improves quality of life. Stroke 2004;35:2477–83.
Barber PA, Demchuk AM, Zhang J, et al. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score. Lancet (London, England) 2000;355:1670–4.
Hurford R, Li L, Lovett N, et al. Prognostic value of “tissue- based” definitions of TIA and minor stroke: population-based study. Neurology 2019;92:e2455–e2461.
Markus HS. Cerebral perfusion and stroke. J Neurol Neurosurg Psychiatry 2004;75:353–61.
Rocha M, Jovin TG. Fast versus slow progressors of infarct growth in large vessel occlusion stroke: clinical and research implications. Stroke 2017;48:2621–7.
National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333:1581–7.
Hacke W, Kaste M, Bluhmki E, et al. Throm- bolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008;359:1317–29.
Rimmele D, Thomalla G. Wake up stroke; clinical characteristics, imaging findings, and treatment option: an update. Front Neurol 2014;5:35.
Thomalla G, Simonsen CZ, Boutite F et al. MRI Guided throm- bolysis for stroke with unknown time of onset. N Eng J Med 2018;379:611–22.
Campbell BCV, Ma H, Ringleb PA et al. Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a system- atic review and meta-analysis of individual patient data. Lancet 2019;394;139–47.
Thomalla G, Boutitie F, Ma H et al. Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging; system- atic review and meta-analysis of individual patient data. Lancet 2020:6736:32163–2.
Burgos AM, Saver JL. Evidence that tenecteplase is noninferior to alteplase for acute ischemic stroke meta-analysis of 5 randomized trials. Stroke 2019;50:2156–62.
Campbell BCV, Mitchell PJ, Churilov L et al. Tenecteplase versus alteplase before thrombectomy for ischemic stroke. N Engl J Med 2018;378:1573–82.
Alamowitch S, Turc G, Palaiodimou L et al. European Stroke Organisation (ESO) expedited recommendation on tenecteplase for acute ischaemic stroke. Eur Stroke J. 2023 Mar;8(1):8-54. doi: 10.1177/23969873221150022. Epub 2023 Feb 2. PMID: 37021186; PMCID: PMC10069183.
Pierot L, Soize S, Benaissa A et al. Techniques for endovascular treatment of acute ischemic stroke: from intra-arterial fibri- nolytics to stent-retrievers. Stroke. 2015 Mar;46(3):909-14. doi: 10.1161/STROKEAHA.114.007935.
Fransen PS, Beumer D, Berkhemer OA; MR CLEAN Investigators, et al. MR CLEAN, a multi- center randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomi- zed controlled trial. Trials. 2014 Sep 1;15:343. doi: 10.1186/1745- 6215-15-343. PMID: 25179366; PMCID: PMC4162915.
Campbell BC, Mitchell PJ, Kleinig TJ; EXTEND-IA Investigators et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015 Mar 12;372(11):1009-18. doi: 10.1056/NEJMoa1414792. Epub 2015 Feb 11. PMID: 25671797.
Goyal M, Demchuk AM, Menon BK; ESCAPE Trial Investigators et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015 Mar 12;372(11):1019-30. doi: 10.1056/NEJMoa1414905. Epub 2015 Feb 11. PMID: 25671798.
Jovin TG, Chamorro A, Cobo E; REVASCAT Trial Investigators et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015 Jun 11;372(24):2296-306. doi: 10.1056/NEJMoa1503780. Epub 2015 Apr 17. PMID: 25882510.
Saver JL, Goyal M, Bonafe A; SWIFT PRIME Investigators et al. Stent-retriever thrombectomy after intra- venous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015 Jun 11;372(24):2285-95. doi: 10.1056/NEJMoa1415061. Epub 2015 Apr 17. PMID: 25882376.
GoyalM, MenonBK, vanZwamWH; HERMES collaborators, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016 Apr 23;387(10029):1723-31. doi: 10.1016/S0140-6736(16)00163-X. Epub 2016 Feb 18. PMID: 26898852.
Gürkaş. E. Uyanma inmeleri ve 6 saat sonrası başvuran akut inmelerde endovasküler tedavi. Müngen B, Özdemir AÖ, editörler. Akut İskemik İnmede Endovasküler Revaskülarizasyon. 1. Baskı. Ankara: Türkiye Klinikleri; 2019. p.7-10.
NogueiraRG, JadhavAP, HaussenDC; DAWN Trial Investigators et al. Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. N Engl J Med. 2018 Jan 4;378(1):11-21. doi: 10.1056/NEJMoa1706442. Epub 2017 Nov 11. PMID: 29129157.
AlbersGW, MarksMP, KempS; DEFUSE 3 Investigators, et al. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. N Engl J Med. 2018 Feb 22;378(8):708-718. doi: 10.1056/NEJMoa1713973. Epub 2018 Jan 24. PMID: 29364767; PMCID: PMC6590673.
Bhalla A, Patel M, Birns J. An update on hyper-acute management of ischaemic stroke. Clin Med (Lond). 2021 May;21(3):215-221. doi: 10.7861/clinmed.2020-0998. Epub 2021 May 4. PMID: 33947658; PMCID: PMC8140712.
Langhorne P, Ramachandra S. Organised inpatient (stroke unit) care for stroke: network meta-analysis. Cochrane Database Syst Rev 2020;4:CD000197.
Fisher M, Bastan B. Identifying and utilizing the ischemic penumbra. Neurology 2012;79:S79–85.
Hurford R, Sekhar A, Hughes TAT, Muir KW. Diagnosis and management of acute ischaemic stroke. Pract Neurol. 2020 Aug;20(4):304-316. doi: 10.1136/practneurol-2020-002557.
Hankey GJ. Stroke. Lancet 2017;389:641–54.
Powers WJ, Rabinstein AA, Ackerson T, et al. Guidelines for the early management of patients with acute ischemic stroke: 2019 update to the 2018 Guidelines for the Early Management of Acute Ischemic Stroke: A Guideline for Healthcare Professionals from the American Heart Associa- tion/American Stroke Association. Stroke 2019;50: e344–418.
Brazzelli M, Shuler K, Quayyum Z, et al. Clinical and imaging services for TIA and minor stroke: results of two surveys of practice across the UK. BMJ Open 2013;3(8).
Wardlaw JM, Seymour J, Cairns J, et al. Immediate computed tomography scanning of acute stroke is cost-effective and improves quality of life. Stroke 2004;35:2477–83.
Barber PA, Demchuk AM, Zhang J, et al. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score. Lancet (London, England) 2000;355:1670–4.
Hurford R, Li L, Lovett N, et al. Prognostic value of “tissue- based” definitions of TIA and minor stroke: population-based study. Neurology 2019;92:e2455–e2461.
Markus HS. Cerebral perfusion and stroke. J Neurol Neurosurg Psychiatry 2004;75:353–61.
Rocha M, Jovin TG. Fast versus slow progressors of infarct growth in large vessel occlusion stroke: clinical and research implications. Stroke 2017;48:2621–7.
National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995;333:1581–7.
Hacke W, Kaste M, Bluhmki E, et al. Throm- bolysis with alteplase 3 to 4.5 hours after acute ischemic stroke. N Engl J Med 2008;359:1317–29.
Rimmele D, Thomalla G. Wake up stroke; clinical characteristics, imaging findings, and treatment option: an update. Front Neurol 2014;5:35.
Thomalla G, Simonsen CZ, Boutite F et al. MRI Guided throm- bolysis for stroke with unknown time of onset. N Eng J Med 2018;379:611–22.
Campbell BCV, Ma H, Ringleb PA et al. Extending thrombolysis to 4·5–9 h and wake-up stroke using perfusion imaging: a system- atic review and meta-analysis of individual patient data. Lancet 2019;394;139–47.
Thomalla G, Boutitie F, Ma H et al. Intravenous alteplase for stroke with unknown time of onset guided by advanced imaging; system- atic review and meta-analysis of individual patient data. Lancet 2020:6736:32163–2.
Burgos AM, Saver JL. Evidence that tenecteplase is noninferior to alteplase for acute ischemic stroke meta-analysis of 5 randomized trials. Stroke 2019;50:2156–62.
Campbell BCV, Mitchell PJ, Churilov L et al. Tenecteplase versus alteplase before thrombectomy for ischemic stroke. N Engl J Med 2018;378:1573–82.
Alamowitch S, Turc G, Palaiodimou L et al. European Stroke Organisation (ESO) expedited recommendation on tenecteplase for acute ischaemic stroke. Eur Stroke J. 2023 Mar;8(1):8-54. doi: 10.1177/23969873221150022. Epub 2023 Feb 2. PMID: 37021186; PMCID: PMC10069183.
Pierot L, Soize S, Benaissa A et al. Techniques for endovascular treatment of acute ischemic stroke: from intra-arterial fibri- nolytics to stent-retrievers. Stroke. 2015 Mar;46(3):909-14. doi: 10.1161/STROKEAHA.114.007935.
Fransen PS, Beumer D, Berkhemer OA; MR CLEAN Investigators, et al. MR CLEAN, a multi- center randomized clinical trial of endovascular treatment for acute ischemic stroke in the Netherlands: study protocol for a randomi- zed controlled trial. Trials. 2014 Sep 1;15:343. doi: 10.1186/1745- 6215-15-343. PMID: 25179366; PMCID: PMC4162915.
Campbell BC, Mitchell PJ, Kleinig TJ; EXTEND-IA Investigators et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med. 2015 Mar 12;372(11):1009-18. doi: 10.1056/NEJMoa1414792. Epub 2015 Feb 11. PMID: 25671797.
Goyal M, Demchuk AM, Menon BK; ESCAPE Trial Investigators et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015 Mar 12;372(11):1019-30. doi: 10.1056/NEJMoa1414905. Epub 2015 Feb 11. PMID: 25671798.
Jovin TG, Chamorro A, Cobo E; REVASCAT Trial Investigators et al. Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med. 2015 Jun 11;372(24):2296-306. doi: 10.1056/NEJMoa1503780. Epub 2015 Apr 17. PMID: 25882510.
Saver JL, Goyal M, Bonafe A; SWIFT PRIME Investigators et al. Stent-retriever thrombectomy after intra- venous t-PA vs. t-PA alone in stroke. N Engl J Med. 2015 Jun 11;372(24):2285-95. doi: 10.1056/NEJMoa1415061. Epub 2015 Apr 17. PMID: 25882376.
GoyalM, MenonBK, vanZwamWH; HERMES collaborators, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016 Apr 23;387(10029):1723-31. doi: 10.1016/S0140-6736(16)00163-X. Epub 2016 Feb 18. PMID: 26898852.
Gürkaş. E. Uyanma inmeleri ve 6 saat sonrası başvuran akut inmelerde endovasküler tedavi. Müngen B, Özdemir AÖ, editörler. Akut İskemik İnmede Endovasküler Revaskülarizasyon. 1. Baskı. Ankara: Türkiye Klinikleri; 2019. p.7-10.
NogueiraRG, JadhavAP, HaussenDC; DAWN Trial Investigators et al. Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct. N Engl J Med. 2018 Jan 4;378(1):11-21. doi: 10.1056/NEJMoa1706442. Epub 2017 Nov 11. PMID: 29129157.
AlbersGW, MarksMP, KempS; DEFUSE 3 Investigators, et al. Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging. N Engl J Med. 2018 Feb 22;378(8):708-718. doi: 10.1056/NEJMoa1713973. Epub 2018 Jan 24. PMID: 29364767; PMCID: PMC6590673.
Bhalla A, Patel M, Birns J. An update on hyper-acute management of ischaemic stroke. Clin Med (Lond). 2021 May;21(3):215-221. doi: 10.7861/clinmed.2020-0998. Epub 2021 May 4. PMID: 33947658; PMCID: PMC8140712.
Langhorne P, Ramachandra S. Organised inpatient (stroke unit) care for stroke: network meta-analysis. Cochrane Database Syst Rev 2020;4:CD000197.
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May 3, 2024
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Önalan A, Gürkaş E. Akut İskemik İnmeye Yaklaşım. In: Külahçıoğlu Ş, Altay S, editors. Kardiyoloji Yoğun Bakım [Internet]. Türkiye: Academician Publishing Book DOI Portal; 2024 [cited 2026 Jul. 13]. pp. 273-82. Available from: https://omp35.books.akademisyen.net/index.php/akya/catalog/book/3049/chapter/13147
