Primer Hiperparatiroidizm
References
Bilezikian JP, Cusano NE, Khan AA, et al. Primary hyperparathyroidism. Nat Rev Dis Primers. 2016 May 19;2:16033. doi: 10.1038/nrdp.2016.33.
Pokhrel B, Leslie SW, Levine SN. Primary Hyperparathyroidism. [Updated 2022 Nov 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441895/
Bilezikian JP, Brandi ML, Eastell R, et al. Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop. J Clin Endocrinol Metab. 2014 Oct;99(10):3561-9. doi: 10.1210/jc.2014-1413.
Wilhelm SM, Wang TS, Ruan DT, et al. The American Association of Endocrine Surgeons Guidelines for Definitive Management of Primary Hyperparathyroidism. JAMA Surg. 2016 Oct 1;151(10):959-968. doi: 10.1001/jamasurg.2016.2310.
Hyperparathyroidism (primary): diagnosis, assessment and initial management. London: National Institute for Health and Care Excellence (NICE); 2019 May 23. (NICE Guideline, No. 132.) Available from: https://www.ncbi.nlm.nih.gov/books/NBK542087/
Mollerup CL, Vestergaard P, Frøkjaer VG, et al. Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled retrospective follow up study. BMJ. 2002 Oct 12;325(7368):807. doi: 10.1136/bmj.325.7368.807.
Silverberg SJ, Shane E, Jacobs TP, et al. A 10-year prospective study of primary hyperparathyroidism with or without parathyroid surgery. N Engl J Med. 1999 Oct 21;341(17):1249-55. doi: 10.1056/NEJM199910213411701.
Castellano E, Tassone F, Attanasio R, et al. Mild primary hyperparathyroidism as defined in the Italian Society of Endocrinology's Consensus Statement: prevalence and clinical features. J Endocrinol Invest. 2016 Mar;39(3):349-54. doi: 10.1007/s40618-015-0412-6.
Lundstam K, Heck A, Mollerup C, et al.; SIPH Study Group. Effects of parathyroidectomy versus observation on the development of vertebral fractures in mild primary hyperparathyroidism. J Clin Endocrinol Metab. 2015 Apr;100(4):1359-67. doi: 10.1210/jc.2014-3441.
McMahon DJ, Carrelli A, Palmeri N, et al. Effect of Parathyroidectomy Upon Left Ventricular Mass in Primary Hyperparathyroidism: A Meta-Analysis. J Clin Endocrinol Metab. 2015 Dec;100(12):4399-407. doi: 10.1210/jc.2015-3202.
Lind L, Jacobsson S, Palmér M, et al. Cardiovascular risk factors in primary hyperparathyroidism: a 15-year follow-up of operated and unoperated cases. J Intern Med. 1991 Jul;230(1):29-35. doi: 10.1111/j.1365-2796.1991.tb00403.x.
Silverberg SJ. Non-classical target organs in primary hyperparathyroidism. J Bone Miner Res. 2002 Nov;17 Suppl 2:N117-25.
Talpos GB, Bone HG 3rd, Kleerekoper M, et al. Randomized trial of parathyroidectomy in mild asymptomatic primary hyperparathyroidism: patient description and effects on the SF-36 health survey. Surgery. 2000 Dec;128(6):1013-20;discussion 1020-1. doi: 10.1067/msy.2000.110844.
Bollerslev J, Jansson S, Mollerup CL, et al. Medical observation, compared with parathyroidectomy, for asymptomatic primary hyperparathyroidism: a prospective, randomized trial. J Clin Endocrinol Metab. 2007 May;92(5):1687-92. doi: 10.1210/jc.2006-1836.
Ambrogini E, Cetani F, Cianferotti L, et al. Surgery or surveillance for mild asymptomatic primary hyperparathyroidism: a prospective, randomized clinical trial. J Clin Endocrinol Metab. 2007 Aug;92(8):3114-21. doi: 10.1210/jc.2007-0219.
Kiriakopoulos A, Petralias A, Linos D. Classic Primary Hyperparathyroidism Versus Normocalcemic and Normohormonal Variants: Do They Really Differ? World J Surg. 2018 Apr;42(4):992-997. doi: 10.1007/s00268-018-4512-2.
Applewhite MK, White MG, Tseng J, et al. Normohormonal primary hyperparathyroidism is a distinct form of primary hyperparathyroidism. Surgery. 2017 Jan;161(1):62-69. doi: 10.1016/j.surg.2016.03.038.
Poppe K, Pipeleers-Marichal M, Flamen P, et al. Non-secreting atypical parathyroid adenoma. J Endocrinol Invest. 2001 Feb;24(2):107-10. doi: 10.1007/BF03343823.
Kunstman JW, Kirsch JD, Mahajan A, et al. Clinical review: Parathyroid localization and implications for clinical management. J Clin Endocrinol Metab. 2013 Mar;98(3):902-12. doi: 10.1210/jc.2012-3168.
Ruda JM, Hollenbeak CS, Stack BC Jr. A systematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003. Otolaryngol Head Neck Surg. 2005 Mar;132(3):359-72. doi: 10.1016/j.otohns.2004.10.005.
Wei WJ, Shen CT, Song HJ, et al. Comparison of SPET/CT, SPET and planar imaging using 99mTc-MIBI as independent techniques to support minimally invasive parathyroidectomy in primary hyperparathyroidism: A meta-analysis. Hell J Nucl Med. 2015 May-Aug;18(2):127-35. doi: 10.1967/s002449910207.
Bunch PM, Kelly HR. Preoperative Imaging Techniques in Primary Hyperparathyroidism: A Review. JAMA Otolaryngol Head Neck Surg. 2018 Oct 1;144(10):929-937. doi: 10.1001/jamaoto.2018.1671.
Liddy S, Worsley D, Torreggiani W, et al. Preoperative Imaging in Primary Hyperparathyroidism: Literature Review and Recommendations. Can Assoc Radiol J. 2017 Feb;68(1):47-55. doi: 10.1016/j.carj.2016.07.004.
Aschenbach R, Tuda S, Lamster E, et al. Dynamic magnetic resonance angiography for localization of hyperfunctioning parathyroid glands in the reoperative neck. Eur J Radiol. 2012 Nov;81(11):3371-7. doi: 10.1016/j.ejrad.2012.05.023.
Beheshti M, Hehenwarter L, Paymani Z, et al. 18F-Fluorocholine PET/CT in the assessment of primary hyperparathyroidism compared with 99mTc-MIBI or 99mTc-tetrofosmin SPECT/CT: a prospective dual-centre study in 100 patients. Eur J Nucl Med Mol Imaging. 2018 Sep;45(10):1762-1771. doi: 10.1007/s00259-018-3980-9.
Ersoy R, Ersoy O, Evranos Ogmen B, et al. Diagnostic value of endoscopic ultrasonography for preoperative localization of parathyroid adenomas. Endocrine. 2014 Sep;47(1):221-6. doi: 10.1007/s12020-013-0152-3.
de la Quintana Basarrate A, Díaz Aguirregoitia FJ, Gil Sánchez J, et al. Valor de la ecoendoscopia transesofágica en el diagnóstico de localización en el hiperparatiroidismo primario [Oesophageal endoscopic ultrasound in the accurate location of primary hyperparathyroidism (HPT)]. Cir Esp. 2009 Jun;85(6):360-4. Spanish. doi: 10.1016/j.ciresp.2008.12.010.
Alvarado R, Meyer-Rochow G, Sywak M, et al. Bilateral internal jugular venous sampling for parathyroid hormone determination in patients with nonlocalizing primary hyperparathyroidism. World J Surg. 2010 Jun;34(6):1299-303. doi: 10.1007/s00268-010-0556-7.
Ibraheem K, Toraih EA, Haddad AB, et al. Selective parathyroid venous sampling in primary hyperparathyroidism: A systematic review and meta-analysis. Laryngoscope. 2018 Nov;128(11):2662-2667. doi: 10.1002/lary.27213.
Henry JF, Defechereux T, Gramatica L, et al. Minimally invasive videoscopic parathyroidectomy by lateral approach. Langenbecks Arch Surg. 1999 Jun;384(3):298-301. doi: 10.1007/s004230050207.
Miccoli P, Berti P, Materazzi G, et al. Minimally invasive video assisted parathyroidectomy (MIVAP). Eur J Surg Oncol. 2003 Mar;29(2):188-90. Miccoli P, Berti P, Materazzi G, Donatini G. Minimally invasive video assisted parathyroidectomy (MIVAP). Eur J Surg Oncol. 2003 Mar;29(2):188-90. doi: 10.1053/ejso.2002.1313.
Udelsman R, Lin Z, Donovan P. The superiority of minimally invasive parathyroidectomy based on 1650 consecutive patients with primary hyperparathyroidism. Ann Surg. 2011 Mar;253(3):585-91. doi: 10.1097/SLA.0b013e318208fed9.
Ahmadieh H, Kreidieh O, Akl EA, et al. Minimally invasive parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IOPTH) and preoperative imaging versus bilateral neck exploration for primary hyperparathyroidism in adults. Cochrane Database Syst Rev. 2020 Oct 21;10(10):CD010787. doi: 10.1002/14651858.CD010787.pub2.
Pokhrel B, Leslie SW, Levine SN. Primary Hyperparathyroidism. [Updated 2022 Nov 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441895/
Bilezikian JP, Brandi ML, Eastell R, et al. Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop. J Clin Endocrinol Metab. 2014 Oct;99(10):3561-9. doi: 10.1210/jc.2014-1413.
Wilhelm SM, Wang TS, Ruan DT, et al. The American Association of Endocrine Surgeons Guidelines for Definitive Management of Primary Hyperparathyroidism. JAMA Surg. 2016 Oct 1;151(10):959-968. doi: 10.1001/jamasurg.2016.2310.
Hyperparathyroidism (primary): diagnosis, assessment and initial management. London: National Institute for Health and Care Excellence (NICE); 2019 May 23. (NICE Guideline, No. 132.) Available from: https://www.ncbi.nlm.nih.gov/books/NBK542087/
Mollerup CL, Vestergaard P, Frøkjaer VG, et al. Risk of renal stone events in primary hyperparathyroidism before and after parathyroid surgery: controlled retrospective follow up study. BMJ. 2002 Oct 12;325(7368):807. doi: 10.1136/bmj.325.7368.807.
Silverberg SJ, Shane E, Jacobs TP, et al. A 10-year prospective study of primary hyperparathyroidism with or without parathyroid surgery. N Engl J Med. 1999 Oct 21;341(17):1249-55. doi: 10.1056/NEJM199910213411701.
Castellano E, Tassone F, Attanasio R, et al. Mild primary hyperparathyroidism as defined in the Italian Society of Endocrinology's Consensus Statement: prevalence and clinical features. J Endocrinol Invest. 2016 Mar;39(3):349-54. doi: 10.1007/s40618-015-0412-6.
Lundstam K, Heck A, Mollerup C, et al.; SIPH Study Group. Effects of parathyroidectomy versus observation on the development of vertebral fractures in mild primary hyperparathyroidism. J Clin Endocrinol Metab. 2015 Apr;100(4):1359-67. doi: 10.1210/jc.2014-3441.
McMahon DJ, Carrelli A, Palmeri N, et al. Effect of Parathyroidectomy Upon Left Ventricular Mass in Primary Hyperparathyroidism: A Meta-Analysis. J Clin Endocrinol Metab. 2015 Dec;100(12):4399-407. doi: 10.1210/jc.2015-3202.
Lind L, Jacobsson S, Palmér M, et al. Cardiovascular risk factors in primary hyperparathyroidism: a 15-year follow-up of operated and unoperated cases. J Intern Med. 1991 Jul;230(1):29-35. doi: 10.1111/j.1365-2796.1991.tb00403.x.
Silverberg SJ. Non-classical target organs in primary hyperparathyroidism. J Bone Miner Res. 2002 Nov;17 Suppl 2:N117-25.
Talpos GB, Bone HG 3rd, Kleerekoper M, et al. Randomized trial of parathyroidectomy in mild asymptomatic primary hyperparathyroidism: patient description and effects on the SF-36 health survey. Surgery. 2000 Dec;128(6):1013-20;discussion 1020-1. doi: 10.1067/msy.2000.110844.
Bollerslev J, Jansson S, Mollerup CL, et al. Medical observation, compared with parathyroidectomy, for asymptomatic primary hyperparathyroidism: a prospective, randomized trial. J Clin Endocrinol Metab. 2007 May;92(5):1687-92. doi: 10.1210/jc.2006-1836.
Ambrogini E, Cetani F, Cianferotti L, et al. Surgery or surveillance for mild asymptomatic primary hyperparathyroidism: a prospective, randomized clinical trial. J Clin Endocrinol Metab. 2007 Aug;92(8):3114-21. doi: 10.1210/jc.2007-0219.
Kiriakopoulos A, Petralias A, Linos D. Classic Primary Hyperparathyroidism Versus Normocalcemic and Normohormonal Variants: Do They Really Differ? World J Surg. 2018 Apr;42(4):992-997. doi: 10.1007/s00268-018-4512-2.
Applewhite MK, White MG, Tseng J, et al. Normohormonal primary hyperparathyroidism is a distinct form of primary hyperparathyroidism. Surgery. 2017 Jan;161(1):62-69. doi: 10.1016/j.surg.2016.03.038.
Poppe K, Pipeleers-Marichal M, Flamen P, et al. Non-secreting atypical parathyroid adenoma. J Endocrinol Invest. 2001 Feb;24(2):107-10. doi: 10.1007/BF03343823.
Kunstman JW, Kirsch JD, Mahajan A, et al. Clinical review: Parathyroid localization and implications for clinical management. J Clin Endocrinol Metab. 2013 Mar;98(3):902-12. doi: 10.1210/jc.2012-3168.
Ruda JM, Hollenbeak CS, Stack BC Jr. A systematic review of the diagnosis and treatment of primary hyperparathyroidism from 1995 to 2003. Otolaryngol Head Neck Surg. 2005 Mar;132(3):359-72. doi: 10.1016/j.otohns.2004.10.005.
Wei WJ, Shen CT, Song HJ, et al. Comparison of SPET/CT, SPET and planar imaging using 99mTc-MIBI as independent techniques to support minimally invasive parathyroidectomy in primary hyperparathyroidism: A meta-analysis. Hell J Nucl Med. 2015 May-Aug;18(2):127-35. doi: 10.1967/s002449910207.
Bunch PM, Kelly HR. Preoperative Imaging Techniques in Primary Hyperparathyroidism: A Review. JAMA Otolaryngol Head Neck Surg. 2018 Oct 1;144(10):929-937. doi: 10.1001/jamaoto.2018.1671.
Liddy S, Worsley D, Torreggiani W, et al. Preoperative Imaging in Primary Hyperparathyroidism: Literature Review and Recommendations. Can Assoc Radiol J. 2017 Feb;68(1):47-55. doi: 10.1016/j.carj.2016.07.004.
Aschenbach R, Tuda S, Lamster E, et al. Dynamic magnetic resonance angiography for localization of hyperfunctioning parathyroid glands in the reoperative neck. Eur J Radiol. 2012 Nov;81(11):3371-7. doi: 10.1016/j.ejrad.2012.05.023.
Beheshti M, Hehenwarter L, Paymani Z, et al. 18F-Fluorocholine PET/CT in the assessment of primary hyperparathyroidism compared with 99mTc-MIBI or 99mTc-tetrofosmin SPECT/CT: a prospective dual-centre study in 100 patients. Eur J Nucl Med Mol Imaging. 2018 Sep;45(10):1762-1771. doi: 10.1007/s00259-018-3980-9.
Ersoy R, Ersoy O, Evranos Ogmen B, et al. Diagnostic value of endoscopic ultrasonography for preoperative localization of parathyroid adenomas. Endocrine. 2014 Sep;47(1):221-6. doi: 10.1007/s12020-013-0152-3.
de la Quintana Basarrate A, Díaz Aguirregoitia FJ, Gil Sánchez J, et al. Valor de la ecoendoscopia transesofágica en el diagnóstico de localización en el hiperparatiroidismo primario [Oesophageal endoscopic ultrasound in the accurate location of primary hyperparathyroidism (HPT)]. Cir Esp. 2009 Jun;85(6):360-4. Spanish. doi: 10.1016/j.ciresp.2008.12.010.
Alvarado R, Meyer-Rochow G, Sywak M, et al. Bilateral internal jugular venous sampling for parathyroid hormone determination in patients with nonlocalizing primary hyperparathyroidism. World J Surg. 2010 Jun;34(6):1299-303. doi: 10.1007/s00268-010-0556-7.
Ibraheem K, Toraih EA, Haddad AB, et al. Selective parathyroid venous sampling in primary hyperparathyroidism: A systematic review and meta-analysis. Laryngoscope. 2018 Nov;128(11):2662-2667. doi: 10.1002/lary.27213.
Henry JF, Defechereux T, Gramatica L, et al. Minimally invasive videoscopic parathyroidectomy by lateral approach. Langenbecks Arch Surg. 1999 Jun;384(3):298-301. doi: 10.1007/s004230050207.
Miccoli P, Berti P, Materazzi G, et al. Minimally invasive video assisted parathyroidectomy (MIVAP). Eur J Surg Oncol. 2003 Mar;29(2):188-90. Miccoli P, Berti P, Materazzi G, Donatini G. Minimally invasive video assisted parathyroidectomy (MIVAP). Eur J Surg Oncol. 2003 Mar;29(2):188-90. doi: 10.1053/ejso.2002.1313.
Udelsman R, Lin Z, Donovan P. The superiority of minimally invasive parathyroidectomy based on 1650 consecutive patients with primary hyperparathyroidism. Ann Surg. 2011 Mar;253(3):585-91. doi: 10.1097/SLA.0b013e318208fed9.
Ahmadieh H, Kreidieh O, Akl EA, et al. Minimally invasive parathyroidectomy guided by intraoperative parathyroid hormone monitoring (IOPTH) and preoperative imaging versus bilateral neck exploration for primary hyperparathyroidism in adults. Cochrane Database Syst Rev. 2020 Oct 21;10(10):CD010787. doi: 10.1002/14651858.CD010787.pub2.
Pages
89-98
Published
April 5, 2023
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Yiğit B, Çiftgez B. Primer Hiperparatiroidizm. In: Alabaz Ö, editor. Güncel Genel Cerrahi Çalışmaları IV [Internet]. Türkiye: Academician Publishing Book DOI Portal; 2023 [cited 2026 Jul. 15]. pp. 89-98. Available from: https://omp35.books.akademisyen.net/index.php/akya/catalog/book/2553/chapter/12757