Radyodirençlilikte GSTP-1 İzoenziminin Olası Rolü: Radyoterapiyle İndüklenen Ros Artışına Yanıt
Referanslar
Jia S, Ge S, Fan X, et al. Promoting reactive oxygen species generation: a key strategy in nanosensitizer-mediated radiotherapy. Nanomedicine (London, England). 2021;16(9):759-78.
Allen C, Her S, Jaffray DA. Radiotherapy for Cancer: Present and Future. Advanced Drug Delivery Reviews. 2017;109:1-2.
Nussbaum DP, Rushing CN, Lane WO, et al. Preoperative or postoperative radiotherapy versus surgery alone for retroperitoneal sarcoma: a case–control, propensity score-matched analysis of a nationwide clinical oncology database. The Lancet Oncology. 2016;17(7):966–75.
Delaney G, Jacob S, Featherstone C, et al. The role of radiotherapy in cancer treatment: estimating optimal utilization from a review of evidence-based clinical guidelines. Cancer. 2005;104(6):1129-37.
Liu Y, Zhang P, Li F, et al. Metal-based nanoenhancers for future radiotherapy: radiosensitizing and synergistic effects on tumor cells. Theranostics. 2018;8(7):1824-49.
Muller C, van der Meulen NP, Benešová M, et al. Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β--Particle, and Auger Electron Emitters. Journal of Nuclear Medicine. 2017;58(Suppl2):91S-96S.
De Ruysscher D, Niedermann G, Burnet NG, et al. Radiotherapy toxicity. Nature Reviews Disease Primers. 2019;5(1):13.
Tan X, Huang X, Niu B, et al. Targeting GSTP1-dependent ferroptosis in lung cancer radiotherapy: Existing evidence and future directions. Frontiers in Molecular Biosciences. 2022;9:1102158.
Kim W, Lee S, Seo D, et al. Cellular Stress Responses in Radiotherapy. Cells. 2019;8(9):1105.
Wang JS, Wang HJ, Qian HL. Biological effects of radiation on cancer cells. Military Medical Research. 2018;30;5(1):20.
Lomax ME, Folkes LK, O'Neill P. Biological consequences of radiation-induced DNA damage: relevance to radiotherapy. Clinical Oncology. 2013;25(10):578-85.
Srinivas US, Tan BWQ, Vellayappan BA, et al. ROS and the DNA damage response in cancer. Redox Biology. 2019;25:101084.
Chatterjee J, Nairy RK, Langhnoja J, et al. ER stress and genomic instability induced by gamma radiation in mice primary cultured glial cells. Metabolic Brain Disease. 2018; 33(3):855-68.
Commoner B, Townsend J, Pake GE. Free radicals in biological materials. Nature. 1954;174(4432): 689-91.
Dahlgren C, Karlsson A. Respiratory burst in human neutrophils. Journal of Immunological Methods. 1999;232(1-2):3-14.
Zhang J, Wang X, Vikash V, et al. ROS and ROS-Mediated Cellular Signaling. Oxidative Medicine and Cellular Longevity. 2016;2016:4350965.
Perry JJ, Shin DS, Getzoff ED, et al. The structural biochemistry of the superoxide dismutases. Biochimica et Biophysica Acta. 2010;1804(2):245-62.
Meitzler JL, Antony S, Wu Y, et al. NADPH oxidases: a perspective on reactive oxygen species production in tumor biology. Antioxidants & Redox Signaling. 2014;20(17):2873-89.
Fransen M, Nordgren M, Wang B, Apanasets O. Role of peroxisomes in ROS/RNS-metabolism: implications for human disease. Biochimica et Biophysica Acta. 2012;1822(9):1363-73.
Ziech D, Franco R, Pappa A, Panayiotidis MI. Reactive oxygen species (ROS)--induced genetic and epigenetic alterations in human carcinogenesis. Mutation Research. 2011;711(1-2):167-73.
Jiang H, Wang H, De Ridder M. Targeting antioxidant enzymes as a radiosensitizing strategy. Cancer Letter. 2018;438:154-64.
Girotti AW. Photosensitized oxidation of membrane lipids: reaction pathways, cytotoxic effects, and cytoprotective mechanisms. Journal of Photochemistry and Photobiology B: Biology. 2001;63(1-3):103-13.
Kammeyer A, Luiten RM. Oxidation events and skin aging. Ageing Research Reviews. 2015;21:16-29.
Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiological Reviews. 2014;94(3):909-50.
Fuchs Y, Steller H. Programmed cell death in animal development and disease. Cell. 2011;147(4):742-58.
Jan R, Chaudhry GE. Understanding Apoptosis and Apoptotic Pathways Targeted Cancer Therapeutics. Advanced Pharmaceutical Bulletin. 2019;9(2):205-18.
Gorski S, Marra M. Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila. Physiological Genomics. 2002;9(2):59-69.
Elmore S. Apoptosis: a review of programmed cell death. Toxicologic Pathology. 2007;35(4):495-516.
Goldar S, Khaniani MS, Derakhshan SM, et al. Molecular mechanisms of apoptosis and roles in cancer development and treatment. Asian Pacific Journal of Cancer Prevention. 2015;16(6):2129-44.
Chang DW, Xing Z, Capacio VL, et al. Interdimer processing mechanism of procaspase-8 activation. EMBO Journal. 2003;22(16):4132-42.
Wang L, Azad N, Kongkaneramit L et al. The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation. Journal of Immunology. 2008;180(5):3072-80.
Kagan VE, Tyurin VA, Jiang J et al. Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors. Nature Chemical Biology. 2005;1(4):223-32.
Li D, Ueta E, Kimura T, et al. Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination. Cancer Science. 2004;95(8):644-50.
Young MM, Takahashi Y, Khan O, et al. Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. Journal of Biological Chemistry. 2012;287(15):12455-68.
Mariño G, Niso-Santano M, Baehrecke EH, et al. Self-consumption: the interplay of autophagy and apoptosis. Nature Reviews Molecular Cell Biology. 2014;15(2):81-94.
Su Z, Yang Z, Xu Y, et al. Apoptosis, autophagy, necroptosis, and cancer metastasis. Molecular Cancer. 2015;21;14-48.
Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nature Cell Biology. 2013;15(7):713-20.
Kim YC, Guan KL. mTOR: a pharmacologic target for autophagy regulation. Journal of Clinical Investigation. 2015;125(1):25-32.
Zhang C, Liu X, Jin S, et al. Ferroptosis in cancer therapy: a novel approach to reversing drug resistance. Molecular Cancer. 2022;21(1):47.
Zhao Y, Li Y, Zhang R, et al. The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy. OncoTargets and Therapy. 2020;13:5429-41.
Tang D, Chen X, Kang R, et al. Ferroptosis: molecular mechanisms and health implications. Cell Research. 2021;31(2):107-25.
Lei G, Zhang Y, Koppula P et al. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Research. 2020;30(2):146-62.
Jia Y, Wang X, Deng Y, et al. Pyroptosis Provides New Strategies for the Treatment of Cancer. Journal of Cancer. 2023;14(1):140-51.
Wang Y, Shi P, Chen Q, et al. Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation. Journal of Molecular Cell Biology. 2019;11(12):1069-82.
Cheng H, Chen L, Huang M, et al. Hunting down NLRP3 inflammasome: An executioner of radiation-induced injury. Frontiers in Immunology. 2022;13:967989.
Zhang Y, Su SS, Zhao S et al. RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome. Nature Communications. 2017;8:14329.
Sharma R, Yang Y, Sharma A, et al. Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis. Antioxidants & Redox Signaling. 2004;6(2):289-300.
Kılıç, M. Küçük Hücreli Dışı Akciğer Karsinomunda Sitokrom P450 ve Glutatyon S-Transferaz İzozimlerinin Gen ve Protein Ekspresyon Düzeylerinin Belirlenmesi. Kırıkkale Üniversitesi Fen Bilimleri Enstitüsü Biyoloji Anabilim Dalı Doktora Tezi. Kırıkkale. 2013 (28.08.2024 tarihinde https://tez.yok.gov.tr/UlusalTezMerkezi/tezSorguSonucYeni.jsp adresinden ulaşılmıştır).
Vural N. Toksikoloji. Ankara: A.Ü. Eczacılık Fakültesi Yayınları No: 73;2005.
Oguztuzun S, Abu-Hijleh A, Coban T, et al. GST isoenzymes in matched normal and neoplastic breast tissue. Neoplasma. 2011;58(4):304-10.
Chatterjee A, Gupta S. The multifaceted role of glutathione S-transferases in cancer. Cancer Letter. 2018:1;433:33-42.
Hayes JD, Flanagan JU, Jowsey IR. Glutathione Transferases, Annual Review of Pharmacology and Toxicology. 2005:45;51-88.
Awasthi YC, Ramana KV, Chaudhary P, et al. Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity. Free Radical Biology and Medicine. 2017;111:235-43.
FeiFei W, HongHai X, YongRong Y, et al. FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression. Cell Death & Disease. 2019:10;351.
van de Wetering C, Elko E, Berg M, et al. Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?. Redox Biology. 2021;43:101995.
Savic-Radojevic A, Mimic-Oka J, Pljesa-Ercegovac M, et al. Glutathione S-transferase-P1 expression correlates with increased antioxidant capacity in transitional cell carcinoma of the urinary bladder. European Urology. 2007;52(2):470-7.
Fang Y, Ye J, Zhao B, et al. Formononetin ameliorates oxaliplatin-induced peripheral neuropathy via the KEAP1-NRF2-GSTP1 axis. Redox Biology. 2020;36:101677.
Zhou H, Zhou YL, Mao JA, et al. NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells. Redox Biology. 2022;55:102413.
Jeong Y, Hoang NT, Lovejoy A, et al. Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance. Cancer Discovery. 2017;7(1):86-101.
Huang Q, Zhong Y, Dong H, et al. Revisiting signal transducer and activator of transcription 3 (STAT3) as an anticancer target and its inhibitor discovery: Where are we and where should we go? European Journal of Medicinal Chemistry. 2020;187:111922.
Fujitani N, Yoneda A, Takahashi M, et al. Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction. Scientific Reports. 2019;9(1):14764.
Pljesa-Ercegovac M, Savic-Radojevic A, Dragicevic D, et al. Enhanced GSTP1 expression in transitional cell carcinoma of urinary bladder is associated with altered apoptotic pathways. Urological Oncology. 2011;29(1):70-7.
Allen C, Her S, Jaffray DA. Radiotherapy for Cancer: Present and Future. Advanced Drug Delivery Reviews. 2017;109:1-2.
Nussbaum DP, Rushing CN, Lane WO, et al. Preoperative or postoperative radiotherapy versus surgery alone for retroperitoneal sarcoma: a case–control, propensity score-matched analysis of a nationwide clinical oncology database. The Lancet Oncology. 2016;17(7):966–75.
Delaney G, Jacob S, Featherstone C, et al. The role of radiotherapy in cancer treatment: estimating optimal utilization from a review of evidence-based clinical guidelines. Cancer. 2005;104(6):1129-37.
Liu Y, Zhang P, Li F, et al. Metal-based nanoenhancers for future radiotherapy: radiosensitizing and synergistic effects on tumor cells. Theranostics. 2018;8(7):1824-49.
Muller C, van der Meulen NP, Benešová M, et al. Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β--Particle, and Auger Electron Emitters. Journal of Nuclear Medicine. 2017;58(Suppl2):91S-96S.
De Ruysscher D, Niedermann G, Burnet NG, et al. Radiotherapy toxicity. Nature Reviews Disease Primers. 2019;5(1):13.
Tan X, Huang X, Niu B, et al. Targeting GSTP1-dependent ferroptosis in lung cancer radiotherapy: Existing evidence and future directions. Frontiers in Molecular Biosciences. 2022;9:1102158.
Kim W, Lee S, Seo D, et al. Cellular Stress Responses in Radiotherapy. Cells. 2019;8(9):1105.
Wang JS, Wang HJ, Qian HL. Biological effects of radiation on cancer cells. Military Medical Research. 2018;30;5(1):20.
Lomax ME, Folkes LK, O'Neill P. Biological consequences of radiation-induced DNA damage: relevance to radiotherapy. Clinical Oncology. 2013;25(10):578-85.
Srinivas US, Tan BWQ, Vellayappan BA, et al. ROS and the DNA damage response in cancer. Redox Biology. 2019;25:101084.
Chatterjee J, Nairy RK, Langhnoja J, et al. ER stress and genomic instability induced by gamma radiation in mice primary cultured glial cells. Metabolic Brain Disease. 2018; 33(3):855-68.
Commoner B, Townsend J, Pake GE. Free radicals in biological materials. Nature. 1954;174(4432): 689-91.
Dahlgren C, Karlsson A. Respiratory burst in human neutrophils. Journal of Immunological Methods. 1999;232(1-2):3-14.
Zhang J, Wang X, Vikash V, et al. ROS and ROS-Mediated Cellular Signaling. Oxidative Medicine and Cellular Longevity. 2016;2016:4350965.
Perry JJ, Shin DS, Getzoff ED, et al. The structural biochemistry of the superoxide dismutases. Biochimica et Biophysica Acta. 2010;1804(2):245-62.
Meitzler JL, Antony S, Wu Y, et al. NADPH oxidases: a perspective on reactive oxygen species production in tumor biology. Antioxidants & Redox Signaling. 2014;20(17):2873-89.
Fransen M, Nordgren M, Wang B, Apanasets O. Role of peroxisomes in ROS/RNS-metabolism: implications for human disease. Biochimica et Biophysica Acta. 2012;1822(9):1363-73.
Ziech D, Franco R, Pappa A, Panayiotidis MI. Reactive oxygen species (ROS)--induced genetic and epigenetic alterations in human carcinogenesis. Mutation Research. 2011;711(1-2):167-73.
Jiang H, Wang H, De Ridder M. Targeting antioxidant enzymes as a radiosensitizing strategy. Cancer Letter. 2018;438:154-64.
Girotti AW. Photosensitized oxidation of membrane lipids: reaction pathways, cytotoxic effects, and cytoprotective mechanisms. Journal of Photochemistry and Photobiology B: Biology. 2001;63(1-3):103-13.
Kammeyer A, Luiten RM. Oxidation events and skin aging. Ageing Research Reviews. 2015;21:16-29.
Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiological Reviews. 2014;94(3):909-50.
Fuchs Y, Steller H. Programmed cell death in animal development and disease. Cell. 2011;147(4):742-58.
Jan R, Chaudhry GE. Understanding Apoptosis and Apoptotic Pathways Targeted Cancer Therapeutics. Advanced Pharmaceutical Bulletin. 2019;9(2):205-18.
Gorski S, Marra M. Programmed cell death takes flight: genetic and genomic approaches to gene discovery in Drosophila. Physiological Genomics. 2002;9(2):59-69.
Elmore S. Apoptosis: a review of programmed cell death. Toxicologic Pathology. 2007;35(4):495-516.
Goldar S, Khaniani MS, Derakhshan SM, et al. Molecular mechanisms of apoptosis and roles in cancer development and treatment. Asian Pacific Journal of Cancer Prevention. 2015;16(6):2129-44.
Chang DW, Xing Z, Capacio VL, et al. Interdimer processing mechanism of procaspase-8 activation. EMBO Journal. 2003;22(16):4132-42.
Wang L, Azad N, Kongkaneramit L et al. The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation. Journal of Immunology. 2008;180(5):3072-80.
Kagan VE, Tyurin VA, Jiang J et al. Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors. Nature Chemical Biology. 2005;1(4):223-32.
Li D, Ueta E, Kimura T, et al. Reactive oxygen species (ROS) control the expression of Bcl-2 family proteins by regulating their phosphorylation and ubiquitination. Cancer Science. 2004;95(8):644-50.
Young MM, Takahashi Y, Khan O, et al. Autophagosomal membrane serves as platform for intracellular death-inducing signaling complex (iDISC)-mediated caspase-8 activation and apoptosis. Journal of Biological Chemistry. 2012;287(15):12455-68.
Mariño G, Niso-Santano M, Baehrecke EH, et al. Self-consumption: the interplay of autophagy and apoptosis. Nature Reviews Molecular Cell Biology. 2014;15(2):81-94.
Su Z, Yang Z, Xu Y, et al. Apoptosis, autophagy, necroptosis, and cancer metastasis. Molecular Cancer. 2015;21;14-48.
Boya P, Reggiori F, Codogno P. Emerging regulation and functions of autophagy. Nature Cell Biology. 2013;15(7):713-20.
Kim YC, Guan KL. mTOR: a pharmacologic target for autophagy regulation. Journal of Clinical Investigation. 2015;125(1):25-32.
Zhang C, Liu X, Jin S, et al. Ferroptosis in cancer therapy: a novel approach to reversing drug resistance. Molecular Cancer. 2022;21(1):47.
Zhao Y, Li Y, Zhang R, et al. The Role of Erastin in Ferroptosis and Its Prospects in Cancer Therapy. OncoTargets and Therapy. 2020;13:5429-41.
Tang D, Chen X, Kang R, et al. Ferroptosis: molecular mechanisms and health implications. Cell Research. 2021;31(2):107-25.
Lei G, Zhang Y, Koppula P et al. The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression. Cell Research. 2020;30(2):146-62.
Jia Y, Wang X, Deng Y, et al. Pyroptosis Provides New Strategies for the Treatment of Cancer. Journal of Cancer. 2023;14(1):140-51.
Wang Y, Shi P, Chen Q, et al. Mitochondrial ROS promote macrophage pyroptosis by inducing GSDMD oxidation. Journal of Molecular Cell Biology. 2019;11(12):1069-82.
Cheng H, Chen L, Huang M, et al. Hunting down NLRP3 inflammasome: An executioner of radiation-induced injury. Frontiers in Immunology. 2022;13:967989.
Zhang Y, Su SS, Zhao S et al. RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome. Nature Communications. 2017;8:14329.
Sharma R, Yang Y, Sharma A, et al. Antioxidant role of glutathione S-transferases: protection against oxidant toxicity and regulation of stress-mediated apoptosis. Antioxidants & Redox Signaling. 2004;6(2):289-300.
Kılıç, M. Küçük Hücreli Dışı Akciğer Karsinomunda Sitokrom P450 ve Glutatyon S-Transferaz İzozimlerinin Gen ve Protein Ekspresyon Düzeylerinin Belirlenmesi. Kırıkkale Üniversitesi Fen Bilimleri Enstitüsü Biyoloji Anabilim Dalı Doktora Tezi. Kırıkkale. 2013 (28.08.2024 tarihinde https://tez.yok.gov.tr/UlusalTezMerkezi/tezSorguSonucYeni.jsp adresinden ulaşılmıştır).
Vural N. Toksikoloji. Ankara: A.Ü. Eczacılık Fakültesi Yayınları No: 73;2005.
Oguztuzun S, Abu-Hijleh A, Coban T, et al. GST isoenzymes in matched normal and neoplastic breast tissue. Neoplasma. 2011;58(4):304-10.
Chatterjee A, Gupta S. The multifaceted role of glutathione S-transferases in cancer. Cancer Letter. 2018:1;433:33-42.
Hayes JD, Flanagan JU, Jowsey IR. Glutathione Transferases, Annual Review of Pharmacology and Toxicology. 2005:45;51-88.
Awasthi YC, Ramana KV, Chaudhary P, et al. Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity. Free Radical Biology and Medicine. 2017;111:235-43.
FeiFei W, HongHai X, YongRong Y, et al. FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression. Cell Death & Disease. 2019:10;351.
van de Wetering C, Elko E, Berg M, et al. Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?. Redox Biology. 2021;43:101995.
Savic-Radojevic A, Mimic-Oka J, Pljesa-Ercegovac M, et al. Glutathione S-transferase-P1 expression correlates with increased antioxidant capacity in transitional cell carcinoma of the urinary bladder. European Urology. 2007;52(2):470-7.
Fang Y, Ye J, Zhao B, et al. Formononetin ameliorates oxaliplatin-induced peripheral neuropathy via the KEAP1-NRF2-GSTP1 axis. Redox Biology. 2020;36:101677.
Zhou H, Zhou YL, Mao JA, et al. NCOA4-mediated ferritinophagy is involved in ionizing radiation-induced ferroptosis of intestinal epithelial cells. Redox Biology. 2022;55:102413.
Jeong Y, Hoang NT, Lovejoy A, et al. Role of KEAP1/NRF2 and TP53 Mutations in Lung Squamous Cell Carcinoma Development and Radiation Resistance. Cancer Discovery. 2017;7(1):86-101.
Huang Q, Zhong Y, Dong H, et al. Revisiting signal transducer and activator of transcription 3 (STAT3) as an anticancer target and its inhibitor discovery: Where are we and where should we go? European Journal of Medicinal Chemistry. 2020;187:111922.
Fujitani N, Yoneda A, Takahashi M, et al. Silencing of Glutathione S-Transferase Pi Inhibits Cancer Cell Growth via Oxidative Stress Induced by Mitochondria Dysfunction. Scientific Reports. 2019;9(1):14764.
Pljesa-Ercegovac M, Savic-Radojevic A, Dragicevic D, et al. Enhanced GSTP1 expression in transitional cell carcinoma of urinary bladder is associated with altered apoptotic pathways. Urological Oncology. 2011;29(1):70-7.
Sayfalar
19-30
Gelecek
27 Ocak 2025
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